For anyone unfamiliar with the product, Crossover Office is a highly polished, commercialized version of Wine. It's main claim to fame is support for running Microsoft Office applications under Linux, but it also supports many additional applications, a very nice front-end and configuration program, and great integration between Linux and Windows apps.
Version 2.0 is an important release because it fixes numerous issues with glibc-2.3, as well as Xfree 4.3. In addition it adds support for Office XP and Photoshop 7, as well as enhanced support for existing Office Apps, Viso, Quicken, and Lotus Notes.
While using FOSS (Free and Open Source Software) is always encouraged, it's an unfortunately fact that some Windows applications will still need to be used. If this is the case for you, then give Crossover Office 2.0 a try. Evaluation copies are available.
Here's a link to the main application page, as well as the change log for what's new in the version.